Who it may suit
- Dull, tired or crepey skin, including under the eyes
- Fine lines and early signs of ageing
- Skin that has lost some firmness or elasticity
- Anyone wanting skin-quality improvement without added volume
GP-led treatment
Polynucleotides for healthier-looking skin
A gradual, skin-quality treatment for texture, fine lines and the delicate under-eye area, with no added volume.
- GP-led care
- Boroughbridge & Billingham
About the treatment
What are polynucleotides?
Polynucleotides are injectable treatments made from highly purified DNA fragments, usually derived from salmon or trout. They aim to improve skin texture, hydration, elasticity and fine lines over time.
They are intended to improve skin quality rather than add volume, which makes them a popular choice for the delicate under-eye area and for anyone wanting fresher, healthier-looking skin.
When it may not be suitable
- An allergy to fish or seafood
- Pregnancy or breastfeeding
- Active infection or inflammation of the skin in the area
- Some medical conditions and medicines, which are checked at consultation
Your full medical history is reviewed at consultation, so this list is a guide only.
Step by step
What to expect
- Consultation: your skin, goals and medical history are assessed, and risks and alternatives are explained.
- Planning: you agree a course of treatment for the face, the eye area or both, and give written consent.
- Treatment: small amounts of product are placed across the area with fine injections. Numbing cream can be used for comfort.
- Course: further sessions are spaced a few weeks apart, with maintenance discussed as your skin responds.
Downtime and recovery
Small raised bumps at the injection points are common and usually settle within a day or two. Redness and occasional bruising are possible, particularly around the eyes.
How long results last
Polynucleotides work gradually, so improvements usually build over the weeks after each session rather than appearing straight away. A course of 3 to 4 sessions is typical, and many people choose maintenance sessions to keep their results. Your practitioner will advise on timing.
Aftercare
- Small bumps at the injection points are expected: leave them alone and they usually settle on their own
- Avoid make-up on the treated area for 12 to 24 hours
- Avoid strenuous exercise, alcohol and extreme heat (saunas, steam rooms, hot yoga) for 24 to 48 hours
- Avoid other facial treatments such as peels, microneedling or laser for around two weeks
- Use a broad-spectrum sun protection factor every day to protect your skin
- Contact the clinic promptly if you notice increasing pain, a change in skin colour, or anything that worries you
If your vision changes after a facial injectable treatment, call 999 or go to A&E straight away and tell them what treatment you have recently had. Do not wait for a reply from the clinic. If you have severe or increasing pain, or the skin turns pale, dusky or blotchy, contact the clinic immediately, or get urgent medical help if you cannot reach us.
Guide prices
Polynucleotides prices
A £25 consultation fee applies and is credited towards treatment when booked within 30 days.
Guide prices
A typical course involves 3 to 4 sessions spaced 3 to 4 weeks apart, with maintenance discussed during consultation.
| Treatment | Price |
|---|---|
| Face (per session) | £199 |
| Face (course of 3) | £550 |
| Eyes (per session) | £175 |
| Eyes (course of 3) | £500 |
Your safety
Clinical standards behind every treatment
The same careful process applies whichever treatment you choose. Read about clinical safety and governance.
GP-led consultation
A face-to-face assessment of your goals, medical history and suitability always comes first.
Consent and time to decide
Risks, alternatives and costs are explained, and you have time to think before giving written consent.
Regulated products, insured care
Medicines are UK-licensed, fillers and skin boosters are CE or UKCA-marked, and the practitioner holds medical indemnity cover.
Aftercare and follow-up
You leave with aftercare advice and a direct way to contact the clinic, with review arranged if needed.
Polynucleotides FAQs
Questions before you book
Are polynucleotides the same as filler?
No. Filler adds volume; polynucleotides aim to improve the quality of the skin itself rather than change the shape of your face. Temporary swelling and small bumps at the injection points can occur.
How many sessions will I need?
A course of 3 to 4 sessions spaced 3 to 4 weeks apart is typical, followed by maintenance if you wish. Your plan will be tailored to your skin.
Can polynucleotides help dark circles?
They may help where thin, crepey skin makes the under-eye area look darker or tired. They are not a treatment for pigmentation or deep hollows, so your consultation will help decide whether they are suitable.
Do polynucleotides hurt?
Most people find them very tolerable. Numbing cream can be used beforehand, and any stinging usually passes quickly.
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Next step
Start with a polynucleotides consultation
Appointments are available at our Boroughbridge clinic and in the Billingham area, by arrangement. Get in touch by WhatsApp or email to find a time that suits you.
Book a Consultation